|“||Welcome to Doctor Who's Line is it Anyway?, the show where everything is made up and the points don't matter, because you will all be exterminated!||”|
— Dalek from Doctor Who's Line is it Anyway?
Lone Rango: The Lone Ranger recruits a chameleon because Tonto is too annoying.
Doctor Who's Line is it Anyway?: The Daleks force the Tenth and Eleventh Doctors to face their greatest challenge yet: improv games.
- MADvent Calendar - Been getting a tan all month? Here are some MAD moments you may have missed:
- Friday, 11:00 AM: The NASA satellite reveals a new view of the sun, reminding NASA researchers you should never look directly at the sun.
- Saturday, 5:00 PM: Everyone is impressed when a zebra and donkey mate to give birth to a zonkey. Everyone except the flamingoat.
- Monday, 8:00 AM: Children going back to school pack their lunches with this!
- Opening Scene
- Lone Rango (Movie Parody of the Lone Ranger and Rango)
- Animated Marginals segment
- Johnny Briefcase (Animated by Mike Wartella)
- The Invisibility Shop (Store parody of PacSun/Ad Parodies segment)
- What If They Had Cell Phones?: Movie Edition - Home Alone, Mary Poppins, and E.T. the Extra Terrestrial (Movie Parody of Home Alone, Disney's Mary Poppins, and E.T. the Extra-Terrestrial)
- Boomerang Bouquet (Cartoon)
- Deadliest Catchy Tune (TV Parody of Deadliest Catch) (Ad Parodies segment)
- Spy vs. Spy - Handbag Bomb (Spy vs. Spy segment) (Stop-motion Cartoon)
- Animated Marginals segment
- Tube Feud (Website Parody of YouTube / Game Show Parody of Family Feud) (Tube Feud segment)
- Quilty as Charged (Animated by Mike Wartella)
- Doctor Who's Line is it Anyway? (TV Parody of Doctor Who and Whose Line is it Anyway?)
- 5-second Cartoon - (from What If They Had Cell Phones?: Movie Edition) E.T. is still on the phone. (5-second Cartoon segment)
- Main article: Lone Rango / Doctor Who's Line is it Anyway?/Gallery
- This is the only time Doctor Who, Whose Line is it Anyway?, and Home Alone showed up.
- Pokey from the Gumby television series appeared in Lone Rango where he acted the part of Silver, the Lone Ranger's white stallion, but he says he is allergic to white paint.
- This is the second time Disney's Mary Poppins, E.T. the Extra-Terrestrial, and Deadliest Catch showed up.
- This is the third time Rango and the Lone Ranger showed up, and the third time a MAD episode comes out on a holiday (Labor Day).
- This is the 53rd time Spy vs. Spy was done in stop-motion, and Black Spy was ahead of White Spy since Episode 9, and also the longest time a spy has gone winning for four months, and the longest consecutive winning streak of a spy, which means Black Spy has won seven times.
- In the actual E.T. film, E.T. dosen't say that much words. He just says "E.T. phone home" and "Ouch."
- Keith Ferguson - Wayne Brady
- Will Friedle - Eleventh Doctor
- Tamara Garfield - Mary Poppins
- Dan Milano - Pokey, Crab Catcher #2, and Michelangelo
- Nolan North - The Lone Ranger and Tenth Doctor
- Rachel Ramras - Jane Banks and Innocent Briefcase
- Kevin Shinick - Dalek, E.T., Quilt, Tonto, Tom Cruise, Butch Cavendish, Johnny Briefcase, and the MADvent Calendar Announcer
- Dana Snyder - Rango, Invisibilty Shop, Husband